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Martin Fusek Selected Research

procathepsin D

2/2013Cathepsin D: Autoantibody profiling as a diagnostic marker for cancers.
4/2012Procathepsin d involvement in chemoresistance of cancer cells.
2/2012Procathepsin D as a tumor marker, anti-cancer drug or screening agent.
10/2008Cathepsin D--many functions of one aspartic protease.
2/2008The propeptide of cathepsin D increases proliferation, invasion and metastasis of breast cancer cells.
7/2007Depletion of procathepsin D gene expression by RNA interference: a potential therapeutic target for breast cancer.
7/2007Procathepsin D expression correlates with invasive and metastatic phenotype of MDA-MB-231 derived cell lines.
6/2007Procathepsin D secreted by HaCaT keratinocyte cells - A novel regulator of keratinocyte growth.
5/2007Ribozyme-targeting procathepsin D and its effect on invasion and growth of breast cancer cells: an implication in breast cancer therapy.
3/2007Secretion of cytokines in breast cancer cells: the molecular mechanism of procathepsin D proliferative effects.
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Martin Fusek Research Topics

Disease

13Neoplasms (Cancer)
02/2013 - 03/2002
9Breast Neoplasms (Breast Cancer)
04/2012 - 03/2002
5Neoplasm Metastasis (Metastasis)
02/2012 - 07/2006
2Carcinoma (Carcinomatosis)
02/2012 - 06/2007
1Fatigue
12/2020
1Necrosis
02/2013
1Lung Neoplasms (Lung Cancer)
11/2006

Drug/Important Bio-Agent (IBA)

14procathepsin DIBA
02/2013 - 03/2002
5Cathepsin DIBA
02/2013 - 05/2007
4Proteins (Proteins, Gene)FDA Link
02/2013 - 11/2006
4Peptides (Polypeptides)IBA
07/2007 - 10/2002
3AntibodiesIBA
04/2012 - 03/2007
3CytokinesIBA
07/2007 - 03/2002
2MitogensIBA
02/2013 - 10/2008
2AutoantibodiesIBA
02/2013 - 02/2012
2Glycoproteins (Glycoprotein)IBA
07/2007 - 10/2002
2Enzyme Precursors (Zymogens)IBA
07/2007 - 05/2007
2Peptide Hydrolases (Proteases)FDA Link
06/2007 - 05/2007
2Interleukin-10 (Interleukin 10)IBA
03/2007 - 03/2002
2Interleukin-4 (Interleukin 4)IBA
03/2007 - 03/2002
2Interleukin-13IBA
03/2007 - 03/2002
1Matrix Metalloproteinases (MMPs)IBA
12/2020
1AntigensIBA
02/2013
1EpitopesIBA
02/2013
1Pharmaceutical PreparationsIBA
02/2012
1Tumor Biomarkers (Tumor Markers)IBA
02/2012
1Amino AcidsFDA Link
02/2008
1Small Interfering RNA (siRNA)IBA
07/2007
1Aspartic Acid ProteasesIBA
07/2007
1Catalytic RNA (Ribozymes)IBA
05/2007
1Interleukin-8 (Interleukin 8)IBA
03/2007
1Estrogen ReceptorsIBA
03/2007
1Complementary DNA (cDNA)IBA
11/2006
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
07/2006
1Cell Surface ReceptorsIBA
07/2006
1NF-kappa B p52 SubunitIBA
07/2006

Therapy/Procedure

3Therapeutics
10/2008 - 05/2007